Bhoyar et al. (2023): Predictive mechanistic modeling of loading and elution in protein A chromatography

Bhoyar, S.; Kumar, V.; Foster, M.; Xu, X.; Traylor, S.; Guo, J.; Lenhoff, A.: Predictive mechanistic modeling of loading and elution in protein A chromatography, Journal of Chromatography A, in press.

CADET used to model proetin A chromatography of monoclonal antibodies with Langmuir and colloidal isotherms, including surface diffusion and pH dependency.

4 Likes

Great work from @soumi!! I very much enjoyed reading the paper and found it to have some creative & novel ideas for model development. The visualizations were also quite aesthetically pleasing.

3 Likes

Thank you for the compliments! :slight_smile:
It was an excellent collaboration.