# Jäpel and Buyel (2022)

**URL:** <https://forum.cadet-web.de/t/japel-and-buyel-2022/1096>\
**Category:** CADET Reference Base\
**Created:** [November 13, 2024, 12:40pm UTC](https://forum.cadet-web.de/t/japel-and-buyel-2022/1096 "2024-11-13T12:40:55Z")\
**Posts on this page:** 1\
**Page:** 1

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**Author:** ![ronald.jaepel](https://forum.cadet-web.de/user_avatar/forum.cadet-web.de/ronald.jaepel/32/986_2.png) [@ronald.jaepel](https://forum.cadet-web.de/u/ronald.jaepel)\
**Post date:** [November 13, 2024, 12:40pm UTC](https://forum.cadet-web.de/t/japel-and-buyel-2022/1096/1 "2024-11-13T12:40:55Z")

</div>

This code reproduces the simulation results and data from [Bayesian optimization using multiple directional objective functions allows the rapid inverse fitting of parameters for chromatography simulations](https://doi.org/10.1016/j.chroma.2022.463408).

Processes can be created for:

1. A non-pore-penetrating tracer experiment
2. A pore-penetrating tracer experiment
3. A series of gradient LWE experiments with the SMA model and one protein component