# Section dependent isotherms and alternative approaches **URL:** \ **Category:** CADET Troubleshooting\ **Created:** [September 19, 2023, 6:09pm UTC](https://forum.cadet-web.de/t/section-dependent-isotherms-and-alternative-approaches/772 "2023-09-19T18:09:28Z")\ **Posts on this page:** 1\ **Showing post:** 6
**Author:** ![alters](https://forum.cadet-web.de/user_avatar/forum.cadet-web.de/alters/32/294_2.png) [@alters](https://forum.cadet-web.de/u/alters)\ **Post date:** [September 21, 2023, 2:04pm UTC](https://forum.cadet-web.de/t/section-dependent-isotherms-and-alternative-approaches/772/6 "2023-09-21T14:04:13Z")
> [@Flynn](#): > > This should be possible. Relevant fields to check are: `write_solution_last_unit` (or `write_solution_last`). This will write the state vectors at the last time point to `last_state_y` in the output group and time derivatives to `last_state_ydot`. Appending `last_state_ydot` to `last_state_y` gives the final vector that can be passed to the next simulation through the `init_state` in the input group. This is actually something @j.breuer and I were discussing recently. I need to follow this exact approach to solve a dilemma described in the earlier post ([Protein at inlet not showing up at outlet - #10 by Flynn](https://forum.cadet-web.de/t/protein-at-inlet-not-showing-up-at-outlet/666/10)). We were not able to figure out a solution (Jan mentioned there might be a problem with consistent initialization). I still have those hdf5 files lying around, so we could look into actually solving the problem again. To be honest, it was a highly atypical application of CADET and using a workaround with running simulations sequentially is totally fine. The ultimate outlet solution already requires three separate simulations, before we implement the workaround. I have another application on the docket that also requires using section-dependent isotherm parameters, so I am interested in the outcome of your investigation @Flynn. --- _[View the full topic](https://forum.cadet-web.de/t/section-dependent-isotherms-and-alternative-approaches/772)._