# \#development

**URL:** https://forum.cadet-web.de/tag/development/3.md

[Latest](https://forum.cadet-web.de/latest.md) · [Categories](https://forum.cadet-web.de/categories.md) · [Tags](https://forum.cadet-web.de/tags.md)

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## [Examples to use gACT isotherm for (multimodal) cation exchange chromatography with split peaks](https://forum.cadet-web.de/t/examples-to-use-gact-isotherm-for-multimodal-cation-exchange-chromatography-with-split-peaks/1428)

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**Author:** [@Flynn](https://forum.cadet-web.de/u/Flynn)\
**Replies:** 1\
**Last updated:** [May 18, 2026, 8:30pm UTC](https://forum.cadet-web.de/t/examples-to-use-gact-isotherm-for-multimodal-cation-exchange-chromatography-with-split-peaks/1428 "2026-05-18T20:30:20Z")

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Background As I discussed in the Recovery conference, the design philosophy of ACT isotherm goes far beyond affinity chromatography. In theory, it can be applied to any modes of chromatography as detailed in the paper Ap…

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## [CADET installation issue mac M3](https://forum.cadet-web.de/t/cadet-installation-issue-mac-m3/1157)

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**Author:** [@naveen567](https://forum.cadet-web.de/u/naveen567)\
**Replies:** 4\
**Last updated:** [September 19, 2025, 7:56am UTC](https://forum.cadet-web.de/t/cadet-installation-issue-mac-m3/1157 "2025-09-19T07:56:38Z")

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Hi all, I attempted to install CADET-core through conda-forge but was unable to do so. When I tried using the Immudzen channel, I encountered an error when importing a cadet from cadet-process. I would appreciate your a…

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## [Batch Elution Chromatography Example](https://forum.cadet-web.de/t/batch-elution-chromatography-example/1281)

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**Author:** [@sasha\_onfleek1](https://forum.cadet-web.de/u/sasha_onfleek1)\
**Replies:** 4\
**Last updated:** [July 22, 2025, 11:41am UTC](https://forum.cadet-web.de/t/batch-elution-chromatography-example/1281 "2025-07-22T11:41:26Z")

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Expected behavior. Heelo! I am new to this and I’m trying to run the first example of CADET Process. I have created an environment (cadet\_env) where I have installed the cadet core and the cadet process (all through cond…

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## [\[Guide\] Particle size distributions in CADET-Process General Rate Model](https://forum.cadet-web.de/t/guide-particle-size-distributions-in-cadet-process-general-rate-model/1135)

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**Author:** [@nbarry03](https://forum.cadet-web.de/u/nbarry03)\
**Replies:** 0\
**Last updated:** [January 20, 2025, 3:49pm UTC](https://forum.cadet-web.de/t/guide-particle-size-distributions-in-cadet-process-general-rate-model/1135 "2025-01-20T15:49:36Z")

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Hi all, I’m writing this on recommendation from some of the CADET devs (thanks @j.schmoelder and @ronald.jaepel!) for anyone who may be looking for a workaround to incorporate particle size distributions in their Genera…

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## [Adapting GRM to membrane chromatography](https://forum.cadet-web.de/t/adapting-grm-to-membrane-chromatography/1094)

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**Author:** [@rosario.cervellere](https://forum.cadet-web.de/u/rosario.cervellere)\
**Replies:** 4\
**Last updated:** [November 13, 2024, 9:04pm UTC](https://forum.cadet-web.de/t/adapting-grm-to-membrane-chromatography/1094 "2024-11-13T21:04:56Z")

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I want to utilize cadet for simulating membrane chromatography. In doing so I need to get under the hood and make a few changes to the GRM and underlying assumptions. Are there readily available resources that outline th…

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## [Mixed mode binding model development (CaptoMMC) ](https://forum.cadet-web.de/t/mixed-mode-binding-model-development-captommc/935)

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**Author:** [@b.huss](https://forum.cadet-web.de/u/b.huss)\
**Replies:** 4\
**Last updated:** [May 17, 2024, 10:15pm UTC](https://forum.cadet-web.de/t/mixed-mode-binding-model-development-captommc/935 "2024-05-17T22:15:28Z")

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Dear CADET team, I am currently trying to simulate and compare elution curves from mixed-mode chromatography (CaptoMMC) with an established CaptoMMC model in GoSilico. I understand that previous posts on the forum have …

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## [Multi-component colloidal model implementation in CADET](https://forum.cadet-web.de/t/multi-component-colloidal-model-implementation-in-cadet/947)

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**Author:** [@soumi](https://forum.cadet-web.de/u/soumi)\
**Replies:** 6\
**Last updated:** [May 18, 2024, 8:20am UTC](https://forum.cadet-web.de/t/multi-component-colloidal-model-implementation-in-cadet/947 "2024-05-18T08:20:37Z")

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Hello, I had a query about the implementation of the colloidal isotherm with multiple adsorbing components. I don’t think this model is included in the documentation, so I took at look at the github file (link at the b…

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## [Test running (especially in Debug mode)](https://forum.cadet-web.de/t/test-running-especially-in-debug-mode/885)

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**Author:** [@ronald.jaepel](https://forum.cadet-web.de/u/ronald.jaepel)\
**Replies:** 4\
**Last updated:** [April 26, 2024, 11:55am UTC](https://forum.cadet-web.de/t/test-running-especially-in-debug-mode/885 "2024-04-26T11:55:05Z")

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If you want to run tests in CADET-Core you need to ensure that in the CMakeSettings.json file: the “cmakeCommandArgs” contain: -DENABLE\_TESTS=ON to enable building the test runner -DENABLE\_STATIC\_LINK\_LAPACK=ON -DENAB…

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## [Kinetic parameter affects the output while kinetics are desabled](https://forum.cadet-web.de/t/kinetic-parameter-affects-the-output-while-kinetics-are-desabled/884)

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**Author:** [@Kats1247](https://forum.cadet-web.de/u/Kats1247)\
**Replies:** 11\
**Last updated:** [April 19, 2024, 7:00am UTC](https://forum.cadet-web.de/t/kinetic-parameter-affects-the-output-while-kinetics-are-desabled/884 "2024-04-19T07:00:37Z")

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Hi, I have registered a custom isotherm model in CADET, that is more or less a Langmuir isotherm (equilibrium approach) with a transformation for gradient runs (organic modifier). While the simulation ran smoothly I no…

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## [Improving the flowrate calculation](https://forum.cadet-web.de/t/improving-the-flowrate-calculation/795)

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**Author:** [@daklauss](https://forum.cadet-web.de/u/daklauss)\
**Replies:** 5\
**Last updated:** [December 1, 2023, 12:57pm UTC](https://forum.cadet-web.de/t/improving-the-flowrate-calculation/795 "2023-12-01T12:57:18Z")

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In the current state, CADET-Process uses sympy to solve the Flow Rates for every unit by creating symbols and generating general equations. This should be improvable by using numpy for solving this problem by generating …

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## [WENO for axisymmetric cylindrical settings](https://forum.cadet-web.de/t/weno-for-axisymmetric-cylindrical-settings/400)

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**Author:** [@s.leweke](https://forum.cadet-web.de/u/s.leweke)\
**Replies:** 13\
**Last updated:** [January 18, 2023, 2:21am UTC](https://forum.cadet-web.de/t/weno-for-axisymmetric-cylindrical-settings/400 "2023-01-18T02:21:28Z")

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Hi there, I’m working on implementing radial flow chromatography models. To this end, I’ve derived the interstitial volume equations as follows: We start with the equation in coordinate-free form: \\frac{\\partial c}{\\…

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## [Model development](https://forum.cadet-web.de/t/model-development/357)

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**Author:** [@Flynn](https://forum.cadet-web.de/u/Flynn)\
**Replies:** 4\
**Last updated:** [July 8, 2021, 2:24pm UTC](https://forum.cadet-web.de/t/model-development/357 "2021-07-08T14:24:20Z")

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Hi CADET team, I’m trying to develop a new isotherm which requires solving non-linear ODEs. I’m not a numerical expert but the equation seems to be similar to Bi-Langmuir or multi-state SMA, please let me know if it’s p…

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## [CADET Build in Ubuntu, in Anaconda base env: cadet-python error: glibc incompatible](https://forum.cadet-web.de/t/cadet-build-in-ubuntu-in-anaconda-base-env-cadet-python-error-glibc-incompatible/363)

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**Author:** [@soumi](https://forum.cadet-web.de/u/soumi)\
**Replies:** 4\
**Last updated:** [July 23, 2021, 11:06pm UTC](https://forum.cadet-web.de/t/cadet-build-in-ubuntu-in-anaconda-base-env-cadet-python-error-glibc-incompatible/363 "2021-07-23T23:06:41Z")

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Hello all, I built CADET on my Linux machine (see “Prerequisites and OS details” at the bottom), and followed it up with the Anaconda instructions mentioned in the tutorial. However, upon trying to install cadet-python …

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## [Slicing global last\_state\_vector\_y in CADET corresponding to each unit operation](https://forum.cadet-web.de/t/slicing-global-last-state-vector-y-in-cadet-corresponding-to-each-unit-operation/331)

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**Author:** [@j.hassan](https://forum.cadet-web.de/u/j.hassan)\
**Replies:** 1\
**Last updated:** [June 2, 2021, 1:21pm UTC](https://forum.cadet-web.de/t/slicing-global-last-state-vector-y-in-cadet-corresponding-to-each-unit-operation/331 "2021-06-02T13:21:12Z")

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Hello CADET Developers, I am trying to understand how the global\_last\_state\_vector\_y is defined and stored in CADET, in order to slice the “last\_state” vector corresponding to each unit operation. According to CADET do…

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## [Moving online documentation into CADET repository](https://forum.cadet-web.de/t/moving-online-documentation-into-cadet-repository/317)

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**Author:** [@s.leweke](https://forum.cadet-web.de/u/s.leweke)\
**Replies:** 4\
**Last updated:** [April 30, 2021, 6:29am UTC](https://forum.cadet-web.de/t/moving-online-documentation-into-cadet-repository/317 "2021-04-30T06:29:08Z")

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As of now, we have two documentations: The TeX / PDF docs in the CADET repository and the website. Although development speed of CADET has decelerated (unfortunately), there are still some changes here and there. In ord…
