Kumar et al. (2021): Robust mechanistic modeling of protein ion-exchange chromatography using a colloidal isotherm

CADET Literature Base
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Kumar, V.; Leweke, S.; Heymann, W.; von Lieres, E.; Schlegel, F.; Westerberg, K.; Lenhoff, A.: Robust mechanistic modeling of protein ion-exchange chromatography using a colloidal isotherm, Journal of Chromatography A 1660 (2021): 462669.

Colloidal isotherm accounts for protein-surface and protein-protein interactions as function of ionic strength and pH. Surface diffusivity depends on ionic strength or binding affinity.

Thanks to Vijesh Kumar, a carefully curated dataset is published with the manuscript.

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Hello everyone,

the abstract to this paper sounds really interesting, but I don’t have a JCA subscription. Can someone share the PDF with me please?

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I have emailed you the manuscript :slight_smile: